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Ophthalmic Res. 2011;46(2):103-6. doi: 10.1159/000323813. Epub 2011 Feb 23.

Canthaxanthin retinopathy: long-term observations.

Author information

1
Centre of Ophthalmology, University Hospital of Cologne, Cologne, Germany. arno.hueber@uni-koeln.de

Abstract

PURPOSE:

To describe the long-term outcome of canthaxanthin retinopathy.

METHODS:

We identified 13 patients with small golden particles near the macular region among a group of 35 patients with known consumption of canthaxanthin somewhen between 1983 and 1988. One long-term follow-up examination was possible in 5 of 13 cases after 16-24 years. The examinations included determination of visual acuity, the Amsler grid, slit lamp examination, perimetry, electro-oculography, electroretinography, optical coherence tomography and fluorescein angiography.

RESULTS:

Complete disappearance of the golden particles took approximately 20 years. The patients in our study were asymptomatic and no functional defect related to canthaxanthin could be detected.

CONCLUSIONS:

Ingestion of canthaxanthin causes no long-term adverse effects.

PMID:
21346389
DOI:
10.1159/000323813
[Indexed for MEDLINE]
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