Coronary angiography remains the gold-standard method for evaluating coronary artery disease and interventional treatments. As percutaneous coronary interventions have advanced, quantitative coronary angiography (QCA) techniques have also evolved in order to provide more accurate assessments of these therapies. Improvements have been made at each step of the QCA process from image acquisition to vessel analysis. In addition, multiple scoring systems have been developed in order to utilize QCA data, both alone and in conjunction with clinical factors, to better stratify patient risk. This article will review the recent advancements in QCA techniques and outcome prediction models.