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Cell. 2011 Feb 18;144(4):467-8. doi: 10.1016/j.cell.2011.01.038.

IL-7 knocks the socs off chronic viral infection.

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Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.


Chronic viral infections represent a major burden to human health, and modulation of the immune system is emerging as a novel approach to fighting such infections. Pellegrini et al. (2011) demonstrate that treatment with the cytokine IL-7 may reinvigorate the immune response to persistent infection by targeting immunosuppressive Socs3 proteins.

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