Asymmetric segregation: the shape of things to come?

Brian K Kennedy; Mark A McCormick

doi:10.1016/j.cub.2011.01.018

Asymmetric segregation: the shape of things to come?

Curr Biol. 2011 Feb 22;21(4):R149-51. doi: 10.1016/j.cub.2011.01.018.

Authors

Brian K Kennedy¹, Mark A McCormick

Affiliation

¹ Buck Institute for Research on Aging, Novato, CA 94945, USA. bkennedy@buckinstitute.org

PMID: 21334292
DOI: 10.1016/j.cub.2011.01.018

Abstract

Yeast mother cells pay a sacrifice during budding: they keep the extrachromosomal rDNA circles (ERCs) so that their buds have a full lifespan ahead. Two new studies indicate that retention of ERCs in mother cells occurs not by tethering to the nuclear periphery but rather by the simple rules of diffusion in a time-limited and complex landscape.

MeSH terms

Cell Division
Diffusion
Gene Expression Regulation, Fungal / physiology*
RNA, Fungal / physiology
RNA, Ribosomal / physiology
Saccharomyces cerevisiae / cytology
Saccharomyces cerevisiae / genetics*
Saccharomyces cerevisiae / metabolism
Time Factors

Substances

RNA, Fungal
RNA, Ribosomal