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Lab Chip. 2011 Apr 7;11(7):1249-55. doi: 10.1039/c0lc00587h. Epub 2011 Feb 17.

Integrated systems for rapid point of care (PoC) blood cell analysis.

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Philips Research Laboratories, 101 Cambridge Science Park, Milton Road, Cambridge CB4 0FY, UK.

Erratum in

  • Lab Chip. 2011 Dec 21;11(24):4279. Green, Nicolas [corrected to Green, Nicolas G].


Counting the different subpopulations of cells in a fingerprick of human blood is important for a number of clinical point-of-care (PoC) applications. It is a challenge to demonstrate the integration of sample preparation and detection techniques in a single platform. In this paper we demonstrate a generic microfluidic platform that combines sample processing and characterisation and enumeration in a single, integrated system. Results of microfluidic 3-part differential leukocyte (granulocyte, lymphocyte and monocyte) counts, together with erythrocyte and thrombocyte (platelet) counts, in human blood are shown and corroborated with results from hospital clinical laboratory analysis.

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