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Transcription. 2011 Jan-Feb;2(1):15-8. doi: 10.4161/trns.2.1.13628.

CarD: a new RNA polymerase modulator in mycobacteria.

Author information

1
Department of Molecular Microbiology, Washington University, St. Louis, MO, USA. stallings@borcim.wustl.edu

Abstract

Mycobacteria CarD is an essential RNAP binding protein that regulates many transcripts including rRNA. This article will review our present state of knowledge regarding CarD and compare the known functions of CarD with other RNAP binding proteins in E. coli, emphasizing how this information can guide future investigations.

KEYWORDS:

CarD; DNA damage; DksA; TRFC; mycobacteria; rRNA; stringent response

PMID:
21326904
PMCID:
PMC3023641
DOI:
10.4161/trns.2.1.13628
[Indexed for MEDLINE]
Free PMC Article

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