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Transcription. 2010 Sep-Oct;1(2):81-4. doi: 10.4161/trns.1.2.12375.

Yin Yang 1: a multifaceted protein beyond a transcription factor.

Author information

1
Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Abstract

As a transcription factor, Yin Yang 1 (YY1) regulates the transcription of a dazzling list of genes and the number of its targets still mounts. Recent studies revealed that YY1 possesses functions independent of its DNA binding activity and its regulatory role in tumorigenesis has started to emerge.

KEYWORDS:

Yin Yang 1; androgen receptor; coactivator; prostate cancer; protein modification; transcription factor

PMID:
21326896
PMCID:
PMC3023633
DOI:
10.4161/trns.1.2.12375
[Indexed for MEDLINE]
Free PMC Article

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