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Transcription. 2010 Sep-Oct;1(2):76-80. doi: 10.4161/trns.1.2.12328.

Illuminating transcription pathways using fluorescent reporter genes and yeast functional genomics.

Author information

1
University of Toronto, ON Canada.

Abstract

Technological advances have enabled researchers to probe gene regulatory pathways on an unprecedented scale. Here, we summarize our recent work that exploits a systematic screening approach in the budding yeast to discover regulators of a promoter of interest. We discuss future applications of our approach based on emerging themes in the literature.

KEYWORDS:

Saccharomyces cerevisiae; gene expression; reporter gene; reporter screens; synthetic genetic array analysis

PMID:
21326895
PMCID:
PMC3023632
DOI:
10.4161/trns.1.2.12328
[Indexed for MEDLINE]
Free PMC Article
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