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Clin Pharmacol Ther. 2011 Mar;89(3):343-5. doi: 10.1038/clpt.2010.303.

Ethical issues in developing pharmacogenetic research partnerships with American Indigenous communities.

Author information

1
Center for Alaska Native Health Research, University of Alaska Fairbanks, Fairbanks, Alaska, USA.

Abstract

Pharmacogenetic research offers the potential to improve the safety and efficacy of drug prescribing. Assuring that the benefits of this research reach indigenous and other medically underserved people is an important justice concern. First, however, a legacy of mistrust, derived from traditional research practices that disempower communities, must be overcome. Linking pharmacogenetic research to collaborative, power-sharing research partnerships provides a valuable opportunity to develop new and positive precedents for genetic research in indigenous communities.

PMID:
21326261
PMCID:
PMC3090734
DOI:
10.1038/clpt.2010.303
[Indexed for MEDLINE]
Free PMC Article

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