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Acta Obstet Gynecol Scand. 2011 Apr;90(4):380-9. doi: 10.1111/j.1600-0412.2011.01071.x. Epub 2011 Mar 4.

Second trimester fetal magnetic resonance imaging improves diagnosis of non-central nervous system anomalies.

Author information

1
Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden. hashem.amini@kbh.uu.se

Abstract

OBJECTIVE:

To evaluate the additional information of second trimester magnetic resonance imaging (MRI) compared with ultrasound in fetuses with identified or suspected non-CNS anomalies and to study the clinical impact of the MRI information on pregnancy management.

DESIGN:

Prospective study during 2003-2007. The fetal MRI examination was planned to be performed within 3 days after the ultrasound.

SETTING:

Uppsala University hospital.

SAMPLE:

Sixty-three women in whom the second trimester ultrasound identified or raised suspicion of fetal anomalies were included.

METHODS:

Ultrasound was compared to MRI in relation to the final diagnosis, which was based on the assessment of all available data, including postpartum clinical follow-up and autopsy results.

MAIN OUTCOME MEASURES:

Evaluation of the additional information gained from MRI and the consequences it had on pregnancy management.

RESULTS:

The mean interval between ultrasound and MRI was 2.6 days (range 0-15 days). In 42 (67%) women MRI was performed within 3 days. All MRI examinations were assessable. In 43 (68%) fetuses MRI provided no additional information, in 17 (27%) MRI added information without changing the management and in three (5%) MRI provided additional information which changed the management. All these three cases had oligohydramnios. In all six cases of diaphragmatic hernia MRI provided additional information.

CONCLUSIONS:

Fetal MRI of non-CNS anomalies in the second trimester seems to be a valuable adjunct to ultrasound diagnosis of non-CNS anomalies, especially in cases of oligohydramnios and diaphragmatic hernia.

[Indexed for MEDLINE]

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