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J Hazard Mater. 2011 Mar 15;187(1-3):596-9. doi: 10.1016/j.jhazmat.2011.01.055. Epub 2011 Jan 18.

Does waterborne citalopram affect the aggressive and sexual behaviour of rainbow trout and guppy?

Author information

1
Department of Physiology/Endocrinology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Box 434, SE-405 30 Göteborg, Sweden.

Abstract

Citalopram is one of several selective serotonin reuptake inhibitors (SSRIs) commonly found in treated sewage effluents. Accordingly, there are concerns about possible adverse effects of SSRIs on aquatic organisms, particularly behavioural effects similar to those associated with SSRI use in humans. Rainbow trout fry and adult male guppies were therefore exposed to waterborne citalopram, ranging from environmentally relevant to high concentrations (1, 10, 100 μg/L) for 3-7 days. Under these experimental conditions citalopram does not appear to cause significant effects on aggression in rainbow trout fry or on sexual behaviour in male guppies. This may be explained by a relatively low uptake of citalopram from water to fish.

PMID:
21300431
DOI:
10.1016/j.jhazmat.2011.01.055
[Indexed for MEDLINE]

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