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South Med J. 2011 Mar;104(3):241-3. doi: 10.1097/SMJ.0b013e31820bfb82.

Low-grade fibromyxoid sarcoma arising in the big toe.

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  • 1Department of Pathology, Specialties Hospital, Hassan II University Hospital, Fez, Morocco.


Low-grade fibromyxoid sarcoma (LGFMS) is a rare neoplasm commonly affecting young adults and typically arising in the somatic soft tissue of the proximal extremities. Its occurrence within the big toe is exceedingly rare. A 43-year-old man had surgery on a mass located in the big toe, which was first noted 6 months previously. Histological examination revealed LGFMS. One year after surgery, the patient is alive with no evidence of disease. Low-grade fibromyxoid sarcoma is a rare neoplasm that should be considered in the differential diagnosis of spindle cell neoplasms of the foot.

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