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Cell Stem Cell. 2011 Feb 4;8(2):122-4. doi: 10.1016/j.stem.2011.01.006.

A comprehensive transcriptional landscape of human hematopoiesis.

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1
Committees on Immunology, Cancer Biology, and Development, Regeneration and Stem Cell Biology, Department of Pathology, The University of Chicago, Chicago, IL 60637, USA. bkee@bsd.uchicago.edu

Abstract

Recently in Cell, Novershtern et al. (2011) reported a comprehensive transcriptome analysis of human hematopoiesis, combined with sophisticated bioinformatics analysis and high-throughput DNA binding data for multiple transcription factors. The resulting map of regulatory interactions controlling stem cell differentiation provides a valuable resource for identification of novel hematopoietic regulators.

PMID:
21295265
DOI:
10.1016/j.stem.2011.01.006
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