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One Hundred Years of Discovery and Rediscovery of Helicobacter pylori and Its Association with Peptic Ulcer Disease.


Marshall BJ.


In: Mobley HLT, Mendz GL, Hazell SL, editors.


Helicobacter pylori: Physiology and Genetics. Washington (DC): ASM Press; 2001. Chapter 3.


Today's understanding of Helicobacter-related gastric diseases in humans stems from an explosion in research, which occurred after the first culture of the organism by Marshall and Warren in 1982 (47). This event may have been the culmination of over 100 years of study of helicobacters and their epiphenomena. This chapter is a concise overview of major highlights during that time following four storylines of spiral bacteria, epidemic gastritis with hypochlorhydria, urease, and bismuth therapy.

Copyright © 2001, ASM Press.

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