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Pediatr Res. 2011 May;69(5 Pt 2):63R-8R. doi: 10.1203/PDR.0b013e318212c2b3.

Structural MRI in autism spectrum disorder.

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1
Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. rong.chen@uphs.upenn.edu

Abstract

Magnetic resonance (MR) examination provides a powerful tool for investigating brain structural changes in children with autism spectrum disorder (ASD). We review recent advances in the understanding of structural MR correlates of ASD. We summarize findings from studies based on voxel-based morphometry, surface-based morphometry, tensor-based morphometry, and diffusion-tensor imaging. Finally, we discuss diagnostic models of ASD based on MR-derived features.

PMID:
21289538
PMCID:
PMC3081653
DOI:
10.1203/PDR.0b013e318212c2b3
[Indexed for MEDLINE]
Free PMC Article
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