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Cell Metab. 2011 Feb 2;13(2):117-8. doi: 10.1016/j.cmet.2011.01.013.

Can dietary nitrates enhance the efficiency of mitochondria?

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Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.


A decline in mitochondrial function occurs in many conditions. A report in this issue of Cell Metabolism (Larsen et al., 2011) shows that dietary inorganic nitrates enhance muscle mitochondrial efficiency. It is an attractive hypothesis that dietary changes enhance energy efficiency, but its potential application depends on long-term studies investigating net benefits versus adverse effects.

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