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Acad Radiol. 2011 Apr;18(4):424-36. doi: 10.1016/j.acra.2010.10.020. Epub 2011 Jan 28.

Imaging of lung cancer in the era of molecular medicine.

Author information

1
Department of Imaging, Dana-Farber Cancer Institute, Boston, MA 02115, USA. mizuki_nishino@dfci.harvard.edu

Abstract

Recent discoveries characterizing the molecular basis of lung cancer brought fundamental changes in lung cancer treatment. The authors review the molecular pathogenesis of lung cancer, including genomic abnormalities, targeted therapies, and resistance mechanisms, and discuss lung cancer imaging with novel techniques. Knowledge of the molecular basis of lung cancer is essential for radiologists to properly interpret imaging and assess response to therapy. Quantitative and functional imaging helps assessing the biologic behavior of lung cancer.

PMID:
21277232
PMCID:
PMC3380440
DOI:
10.1016/j.acra.2010.10.020
[Indexed for MEDLINE]
Free PMC Article

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