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Microbes Infect. 2011 May;13(5):502-15. doi: 10.1016/j.micinf.2011.01.014. Epub 2011 Jan 27.

The contribution of animal models to the understanding of the host range and virulence of influenza A viruses.

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1
Laboratory of Infectious Diseases, NIAID, NIH, Bethesda, MD 20892, USA.

Abstract

Since ferrets were first used in 1933 during the initial isolation of influenza A viruses, animal models have been critical for influenza research. The following review discusses the contribution of mice, ferrets, and non-human primates to the study of influenza virus host range and pathogenicity.

PMID:
21276869
PMCID:
PMC3071864
DOI:
10.1016/j.micinf.2011.01.014
[Indexed for MEDLINE]
Free PMC Article
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