Format

Send to

Choose Destination
Ann N Y Acad Sci. 2011 Jan;1217:191-206. doi: 10.1111/j.1749-6632.2010.05882.x.

Role of TLR2-dependent inflammation in metastatic progression.

Author information

1
Department of Pharmacology and Cancer Center, School of Medicine, University of California, San Diego, La Jolla, California, USA.

Abstract

Inflammation is a part of the host defense system, which provides protection against invading pathogens. However, it has become increasingly clear that inflammation can be evoked by endogenous mediators through Toll-like receptors (TLRs) to enhance tumor progression and metastasis. Here, we discuss the roles of TLR-mediated inflammation in tumor progression and the mechanisms through which it accomplishes this pathogenic function.

PMID:
21276007
PMCID:
PMC4383094
DOI:
10.1111/j.1749-6632.2010.05882.x
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Wiley Icon for PubMed Central
Loading ...
Support Center