Novel dynamic four-dimensional CT angiography revealing 2-type motions of cerebral arteries

Stroke. 2011 Mar;42(3):815-8. doi: 10.1161/STROKEAHA.110.591008. Epub 2011 Jan 27.

Abstract

Background and purpose: We developed a novel dynamic 4-dimensional CT angiography to accurately evaluate dynamics in cerebral aneurysm.

Methods: Dynamic 4-dimensional CT angiography achieved high-resolution 3-dimensional imaging with temporal resolution in a beating heart using dynamic scanning data sets reconstructed with a retrospective simulated R-R interval reconstruction algorithm.

Results: Movie artifacts disappeared on dynamic 4-dimensional CT angiography movies of 2 kinds of stationary phantoms (titanium clips and dry bone). In the virtual pulsating aneurysm model, pulsation on the dynamic 4-dimensional CT angiography movie resembled actual movement in terms of pulsation size. In a clinical study, dynamic 4-dimensional CT angiography showed 2-type motions: pulsation and anatomic positional changes of the cerebral artery.

Conclusions: This newly developed 4-dimensional visualizing technique may deliver some clues to clarify the pathophysiology of cerebral aneurysms.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cerebral Angiography / methods*
  • Cerebral Arteries / diagnostic imaging*
  • Cerebral Arteries / physiopathology
  • Four-Dimensional Computed Tomography / methods*
  • Humans
  • Intracranial Aneurysm / diagnosis*
  • Intracranial Aneurysm / diagnostic imaging*
  • Intracranial Aneurysm / physiopathology
  • Retrospective Studies