Clinical and laboratory findings in 220 children with recurrent abdominal pain

Acta Paediatr. 2011 Jul;100(7):1028-32. doi: 10.1111/j.1651-2227.2011.02179.x. Epub 2011 Feb 22.

Abstract

Aim: To investigate the clinical and laboratory findings in children with recurrent abdominal pain (RAP).

Methods: Consecutive patients with RAP (Apley criteria), age 4-16 years, referred to a secondary medical centre were evaluated by a standardized history, physical examination and laboratory tests. The tests encompassed Helicobacter pylori (Hp), gastrointestinal bacterial infections, protozoa, coeliac disease, carbohydrate malabsorption, food intolerance, abdominal ultrasound and plain abdominal X-ray. More investigations were obtained if indicated. Patient characteristics were compared with surgical patients without abdominal pain (control group).

Results: A total of 220 consecutive patients were included (92 M, mean age 8.8 years [4.1-16.0 years]). In 88% of the patients, abnormalities were found that refer to possible causes. Especially, protozoa were present in 33% of the patients, mostly Dientamoeba fragilis, Yersinia enterocolitica in 12% and endoscopically proven infection with Hp in 11%. In 36%, a plain abdominal X-ray raised suspicion of constipation.

Conclusion: In 220 consecutive patients with RAP, referred to secondary care, a standardized work-up yielded abnormal results in a high percentage. The clinical significance of these findings remains to be established.

MeSH terms

  • Abdominal Pain / etiology*
  • Abdominal Pain / microbiology
  • Abdominal Pain / parasitology
  • Adolescent
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Constipation / complications*
  • Dientamoeba / classification
  • Dientamoeba / isolation & purification
  • Dientamoebiasis / complications*
  • Endoscopy, Gastrointestinal
  • Female
  • Helicobacter Infections / complications*
  • Helicobacter pylori / isolation & purification
  • Humans
  • Male
  • Prospective Studies
  • Radiography, Abdominal
  • Recurrence
  • Referral and Consultation
  • Yersinia Infections / complications*
  • Yersinia enterocolitica / isolation & purification