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Int J Gynaecol Obstet. 2011 Mar;112(3):171-8. doi: 10.1016/j.ijgo.2010.08.025. Epub 2011 Jan 26.

Cost-effectiveness and quality of life associated with heavy menstrual bleeding among women using the levonorgestrel-releasing intrauterine system.

Author information

1
Department of Obstetrics and Gynecology, Stanford University, Stanford, USA.

Abstract

OBJECTIVE:

To review the literature for economic and health-related quality of life outcomes data associated with the use of the levonorgestrel-releasing intrauterine system (LNG-IUS) in the management of heavy menstrual bleeding.

METHODS:

We searched the MEDLINE and EMBASE databases simultaneously using the Ovid interface to review the literature in a systematic manner for economic and health-related quality of life outcomes data associated with the use of the LNG-IUS in women with heavy menstrual bleeding. Articles were then selected for further review based on the relevance of their titles and/or abstracts. We identified 17 articles for inclusion in this review.

RESULTS:

Treating heavy menstrual bleeding with the LNG-IUS was found to be cost-effective in various countries and settings. Moreover, irrespective of the measuring instrument used, health-related quality-of-life outcomes were found to be improved to a degree similar to that achieved with endometrial ablation or hysterectomy. In some cases, the LNG-IUS appeared to be more effective and less costly than the surgical options.

CONCLUSION:

The LNG-IUS is a cost-effective treatment option for heavy menstrual bleeding when pharmacologic treatment is indicated.

PMID:
21269626
DOI:
10.1016/j.ijgo.2010.08.025
[Indexed for MEDLINE]

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