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Dermatol Surg. 2011 Feb;37(2):207-16. doi: 10.1111/j.1524-4725.2010.01854.x. Epub 2011 Jan 26.

Percutaneous collagen induction versus full-concentration trichloroacetic acid in the treatment of atrophic acne scars.

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1
Dermatology Department, Faculty of Medicine Student Hospital, Cairo University, Cairo, Egypt.

Abstract

BACKGROUND:

Percutaneous collagen induction (PCI) promotes removal of damaged collagen and induces more collagen immediately under the epidermis. The chemical reconstruction of skin scars (CROSS) method is a focal application of full-concentration trichloroacetic acid (TCA) to atrophic acne scars. The CROSS method has the advantage of reconstructing acne scars by increasing dermal thickening and collagen production.

OBJECTIVE:

To compare the safety and efficacy of PCI and the 100% TCA CROSS method for the treatment of atrophic acne scars.

MATERIALS AND METHODS:

Thirty participants were randomly equally divided into two groups; group 1 underwent four sessions (4 weeks apart) of PCI, and group 2 underwent four sessions (4 weeks apart) of 100% TCA CROSS.

RESULTS:

Acne scarring improved in 100% of patients. Scar severity scores improved by a mean of 68.3% (p<.001) in group 1 and a mean of 75.3% (p<.001) in group 2. The difference in the degree of improvement was not statistically significant between the groups (p=.47).

CONCLUSIONS:

PCI and 100% TCA CROSS were effective in the treatment of atrophic acne scars.

[Indexed for MEDLINE]

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