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Int J Neurosci. 2011 May;121(5):267-70. doi: 10.3109/00207454.2010.550405. Epub 2011 Jan 26.

Predictors of poor outcome at hospital discharge following a spontaneous intracerebral hemorrhage.

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Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA.



Spontaneous intracranial hemorrhage (S-ICH) often leads to significant morbidity and mortality. Clinical scoring systems can predict the mortality and functional outcome after ICH (FUNC score). FOUR score is a recently developed coma scale that incorporates brainstem reflexes. We propose that the combination of FUNC and FOUR scores will be a better prognostic indicator than either FUNC or FOUR score alone for S-ICH patients.


We conducted a retrospective chart review of all S-ICH patients (>18 years of age) from January 2008 to May 2010. ICH volume was calculated using the ABC/2 formula. FUNC (≤ 5 or >5) and FOUR (≤ 10 and >10) scores were calculated from admission data. Statistical analyses included chi-square test, positive predictive value, and relative risk assessment.


Total number of patients was 92. The mean age of presentation was 64.6 ± 15.6 years (range: 27-95 years). Male to female ratio was 1.6:1. Combined FUNC score ≤ 5 and FOUR score ≤ 10 (F2 score; 95%) had higher positive predictive value for mortality than either FUNC score ≤ 5 (82%) or FOUR score ≤ 10 (81%).


The combination of the FUNC and the FOUR scoring system is a better prognostication indicator for S-ICH patients than either FUNC or FOUR score.

[Indexed for MEDLINE]

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