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Opt Express. 2011 Jan 17;19(2):1217-27. doi: 10.1364/OE.19.001217.

Visualization of microvasculature by dual-beam phase-resolved Doppler optical coherence tomography.

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Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.


We present a dual-beam Doppler optical coherence tomography system for visualizing the microvasculature within the retina. The sample arm beams from two identical spectral domain optical coherence tomography (SD-OCT) systems are combined such that there is a small horizontal offset between them at the retina. Thereby we record two tomograms which are slightly separated in time. Phase-resolved Doppler analysis is performed between these two data sets. This system allows blood capillary imaging with high flow sensitivity and variable velocity range. To demonstrate the performance of our system we present images of the microvascular network around the fovea and around the optic nerve head of the human eye.

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