Regulator of Ras depalmitoylation and retrograde trafficking: a new hat for FKBP

Jun O Liu; Denis V Titov; Yongjun Dang; Qingli He

doi:10.1016/j.molcel.2011.01.009

Regulator of Ras depalmitoylation and retrograde trafficking: a new hat for FKBP

Mol Cell. 2011 Jan 21;41(2):131-3. doi: 10.1016/j.molcel.2011.01.009.

Authors

Jun O Liu¹, Denis V Titov, Yongjun Dang, Qingli He

Affiliation

¹ Department of Pharmacology, Johns Hopkins School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA. joliu@jhu.edu

PMID: 21255722
DOI: 10.1016/j.molcel.2011.01.009

Abstract

In this issue of Molecular Cell, Ahearn et al. (2011) identified FKBP12 as a novel regulator of Ras signaling through its modulation of depalmitoylation of H-Ras and its recycling from plasma membrane to the Golgi.

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