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J Asian Nat Prod Res. 2011 Jan;13(1):80-3. doi: 10.1080/10286020.2010.543131.

Anti-inflammatory flavonolignans from Hydnocarpus anthelminthica seeds.

Author information

1
College of Animal Science and Technology, Yunnan Agricultural University, Kunming, China.

Abstract

A new flavonolignan, anthelminthicol A (1), together with four known compounds, was isolated from the EtOAc extracts of the seeds of Hydnocarpus anthelminthica. Their structures were elucidated using extensive spectroscopic techniques. Bioassay showed that compounds 3-5 could inhibit nitric oxide production in LPS-stimulated RAW 264.7 macrophage cell lines, with IC(50) values of 7.81, 9.38, and 10.55 μM, respectively.

PMID:
21253954
DOI:
10.1080/10286020.2010.543131
[Indexed for MEDLINE]

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