Estimating the impact of human papillomavirus (HPV) vaccination on HPV prevalence and cervical cancer incidence in Mali

Clin Infect Dis. 2011 Mar 1;52(5):641-5. doi: 10.1093/cid/ciq190. Epub 2011 Jan 20.

Abstract

Human papillomavirus vaccines have potential to reduce cervical cancer incidence and mortality; however, cultural and economic barriers may hinder success in developing countries. We assessed impact of a single vaccine campaign in Mali with use of mathematical modeling. Our model shows that decreases in the prevalence of Human papillomavirus infection are proportional to achieved vaccination coverage.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Female
  • Humans
  • Incidence
  • Mali / epidemiology
  • Models, Theoretical
  • Papillomavirus Infections / epidemiology*
  • Papillomavirus Infections / mortality
  • Papillomavirus Infections / prevention & control
  • Papillomavirus Vaccines / administration & dosage*
  • Papillomavirus Vaccines / immunology*
  • Prevalence
  • Uterine Cervical Neoplasms / epidemiology*
  • Uterine Cervical Neoplasms / mortality
  • Uterine Cervical Neoplasms / prevention & control
  • Vaccination / statistics & numerical data*

Substances

  • Papillomavirus Vaccines