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Virology. 2011 Mar 15;411(2):244-50. doi: 10.1016/j.virol.2010.12.024. Epub 2011 Jan 15.

The taking of the cytoskeleton one two three: how viruses utilize the cytoskeleton during egress.

Author information

1
Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA. Brian_Ward@urmc.rochester.edu

Abstract

The final assembly of nonlytic envelope viruses requires the coordinated transport of either subviral particles or fully formed virions to the plasma membrane for release from the cell. Recent research has delved into the mechanisms viruses employ to hijack the host cell's cytoskeletal system for active transport to the site of final assembly and release. This review will look at recent findings that relate to the transport of virions to the cell periphery and out of the cell.

PMID:
21241997
PMCID:
PMC3049855
DOI:
10.1016/j.virol.2010.12.024
[Indexed for MEDLINE]
Free PMC Article

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