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Bull Exp Biol Med. 2011 Jan;150(3):340-2.

Effect of acetylcholine on mortality of mice from sepsis and proinflammatory cytokine production.

Author information

1
Saratov Military Institute of Biological and Chemical Safety, Russia. pz@renet.com.ru

Abstract

Experiments on outbred mice showed that acetylcholine chloride in a dose of 20 mg/kg 6 h after subcutaneous injection significantly reduces mortality of mice from sepsis induced by intraperitoneal injection of 2×10(9) E. coli bacterial bodies and the blood levels of proinflammatory cytokines TNF-α, IL-1β, and IL-6.

PMID:
21240349
[Indexed for MEDLINE]

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