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Dev Cell. 2011 Jan 18;20(1):3-4. doi: 10.1016/j.devcel.2010.12.013.

MicroRNAs sculpt gene expression in embryonic development: new insights from plants.

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Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.


Zygotic microRNAs coordinate the clearance of maternal mRNA in animals to facilitate developmental transitions. In a recent issue of Genes and Development, Nodine and Bartel (2010) uncover a reciprocal function in plants, where miRNA-156 preemptively represses genes that function later in development to prevent premature developmental transitions.

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