Send to

Choose Destination
Trends Ecol Evol. 1995 Aug;10(8):324-8.

The molecular basis of quantitative genetic variation in natural populations.

Author information

Thomas Mitchell-Olds is at the Division of Biological Sciences, University of Montana, Missoula, MT 59812, USA.


DNA markers allow us to study quantitative trait loci (QTL) - the genes that control adaptation and quantitative variation. Experiments can map the genes responsible for quantitative variation and address the evolutionary and ecological significance of this variation. Recent studies suggest that major genes segregate within and among natural populations. It is now feasible to study the genes that cause morphological variation, life history trade-offs, heterosis and speciation. These methods can determine the role of epistasis and genotype-by-environment interaction in maintaining genetic variation. QTL mapping is an important tool used to address evolutionary and ecological questions of long-standing interest.

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center