Format

Send to

Choose Destination
See comment in PubMed Commons below
Adv Chronic Kidney Dis. 2011 Jan;18(1):6-10. doi: 10.1053/j.ackd.2010.11.006.

The attributable burden of hypertension: focus on CKD.

Author information

1
University of Michigan Medical Center, Ann Arbor, MI; and Renal Division, University of Pennsylvania, Philadelphia, PA 48106, USA. jamerson@umich.edu

Abstract

Hypertension is a worldwide risk factor for premature death and disability from heart disease, stroke, peripheral vascular disease, and kidney failure. Much is known about the role of elevated blood pressure as a contributor to diseases of the heart and brain, but the risk it confers specifically to the development and progression of kidney disease is less well appreciated. The kidney is unique among the target organs of elevated blood pressure because it both suffers damage and still contributes to the pathophysiologic sustenance of hypertension through many avenues. In this overview, we discuss high blood pressure from an epidemiologic standpoint, placing it in a nephrologic perspective and discuss some of the known and speculative mechanisms that link it to kidney damage.

PMID:
21224024
DOI:
10.1053/j.ackd.2010.11.006
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center