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Diagn Pathol. 2011 Jan 10;6:4. doi: 10.1186/1746-1596-6-4.

Lymphoepithelioma-like carcinoma of the vulva, an underrecognized entity? Case report with a single inguinal micrometastasis detected by sentinel node technique.

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1
Department of Pathology, Krankenhaus Barmherzige Schwestern, Linz, Austria. hans-christian.boesmueller@bhs.at

Abstract

This report describes an unusual EBV-negative lymphoepithelioma-like carcinoma of the vulva in a 73-year-old patient. The lesion was localised at the right minor labium and was resected by partial vulvectomy. A synchronous sentinel lymph node biopsy revealed a single micrometastasis in the right inguinal region, which prompted local radiotherapy. Follow-up nine months later showed only slight vulvar atrophy, without signs of local recurrence or distant metastases.Although lymphoepithelioma-like carcinomas of the skin and the female genital tract are presumed to have a better prognosis than their counterparts in the upper aerodigestive tract, possibly due to earlier detection and therapy, this case documents their potential for early metastasis.

PMID:
21219641
PMCID:
PMC3023728
DOI:
10.1186/1746-1596-6-4
[Indexed for MEDLINE]
Free PMC Article
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