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Med Mal Infect. 2011 Feb;41(2):97-101. doi: 10.1016/j.medmal.2010.11.008. Epub 2011 Jan 6.

[The re-emergence of pertussis in Tunisia].

[Article in French]

Author information

1
Laboratoire de Microbiologie, Hôpital d'Enfants de Tunis, Tunis, Tunisie. zouariasma1@yahoo.fr

Abstract

OBJECTIVE:

The authors had for aim to analyze pertussis epidemiology in Tunisia by studying nasopharyngeal specimens of infants hospitalized in Tunis.

METHODS:

Between march 2007 and march 2008, clinical nasopharyngeal samples were collected from infants with a suspected diagnosis of whooping cough, pertussoid cough, or pertussis-like syndrome, admitted at the Tunis children's hospital. The laboratory diagnostic criteria were culture isolation of Bordetella species on Bordet-Gengou medium and real-time PCR.

RESULTS:

Fifty-nine percent of the 74 investigated children with suspected pertussis were less than two months of age. The diagnosis of pertussis was proved positive by real-time PCR for 41%. Culture was negative in all cases.

CONCLUSIONS:

Whooping cough is still prevalent in Tunisia despite an important vaccination coverage. Real-time PCR is an invaluable tool for the rapid diagnosis of pertussis, however culture must also be associated.

PMID:
21215539
DOI:
10.1016/j.medmal.2010.11.008
[Indexed for MEDLINE]

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