Send to

Choose Destination
FEBS J. 2011 Mar;278(5):687-703. doi: 10.1111/j.1742-4658.2011.08004.x. Epub 2011 Jan 28.

Macromolecular NMR spectroscopy for the non-spectroscopist.

Author information

School of Molecular Bioscience, University of Sydney, New South Wales, Australia.


NMR spectroscopy is a powerful tool for studying the structure, function and dynamics of biological macromolecules. However, non-spectroscopists often find NMR theory daunting and data interpretation nontrivial. As the first of two back-to-back reviews on NMR spectroscopy aimed at non-spectroscopists, the present review first provides an introduction to the basics of macromolecular NMR spectroscopy, including a discussion of typical sample requirements and what information can be obtained from simple NMR experiments. We then review the use of NMR spectroscopy for determining the 3D structures of macromolecules and examine how to judge the quality of NMR-derived structures.

[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center