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Nat Prod Commun. 2010 Nov;5(11):1743-6.

New steroidal alkaloids from Solanum hypomalacophyllum.

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Laboratoire de Pharmacognosie, UMIB, EA 3660, Faculté de Pharmacie, Université de Bourgogne, 7 Bd Jeanne d'Arc, 21079 Dijon Cedex, France.


Two new steroidal alkaloids (1-2) have been isolated from the leaves and roots of Solanum hypomalacophyllum Bitter, respectively. Their structures have been elucidated as deacetoxysolaphyllidine-3-O-beta-D-glucopyranoside (1) and 4-keto-5,6-dihydro-(20S)-verazine (2). Furthermore, two known steroidal alkaloids, 20R-verazine and 20S-verazine, and the common secondary metabolites oleanolic acid and beta-sitosterol were isolated from the roots, whereas deacetoxysolaphyllidine was obtained from the leaves.

[Indexed for MEDLINE]

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