Send to

Choose Destination
See comment in PubMed Commons below
Ultrason Imaging. 2010 Oct;32(4):255-66.

Dispersion and shear modulus measurements of porcine liver.

Author information

Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.


A narrow-band ultrasonic shear-wave imaging technique for estimating phase speed was applied to fresh and thermally damaged porcine liver in vitro. Two constitutive models were applied to the measurements to represent rheological behavior of the tissue and estimate the complex shear modulus at frequencies between 50 and 300 Hz. Our results were compared to similar values from the literature to assess how well models represent liver measurements over a range of shear-wave frequencies, experimental conditions and mammalian species. We found remarkable consistency in some parameters but not in others, suggesting that the Kelvin-Voigt model commonly applied in elasticity-imaging situations is representative of tissue dispersion but the description it offers is incomplete. Data are consistent with the theory that viscoelastic contrast is more likely due to changes in protein and other biomolecular-scale structures than from tissue anatomy larger than a cell. Dispersion measurements at frequencies between 0.5-1000 kHz are needed to more completely evaluate models for the viscoelastic behavior liver.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Atypon
    Loading ...
    Support Center