Abstract
Experimental evidence on the interaction of liposomes of varying composition with canine serum components has shown that neutral liposomes and those positively and negatively charged bind actively to different serum proteins, among which albumin and heavy and light Ig G chains have been detected. A simple and informative approach to studying the liposome-protein interactions is suggested.
Publication types
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Comparative Study
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English Abstract
MeSH terms
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Animals
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Blood Protein Electrophoresis
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Cholesterol / administration & dosage
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Cholesterol / pharmacology*
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Dogs
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Drug Interactions
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Immunoglobulin G / analysis
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Immunoglobulin G / drug effects*
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Immunoglobulin Light Chains / analysis
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Immunoglobulin Light Chains / drug effects*
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In Vitro Techniques
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Liposomes / administration & dosage
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Liposomes / pharmacology*
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Phosphatidylcholines / administration & dosage
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Phosphatidylcholines / pharmacology*
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Serum Albumin / analysis
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Serum Albumin / drug effects*
Substances
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Immunoglobulin G
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Immunoglobulin Light Chains
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Liposomes
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Phosphatidylcholines
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Serum Albumin
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Cholesterol