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Arthritis Res Ther. 2010;12(6):223. doi: 10.1186/ar3199. Epub 2010 Dec 21.

Epidemiology of gout.

Author information

1
Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University, Staffordshire ST5 5BG, UK. e.roddy@cphc.keele.ac.uk

Abstract

Gout is the most prevalent form of inflammatory arthropathy. Several studies suggest that its prevalence and incidence have risen in recent decades. Numerous risk factors for the development of gout have been established, including hyperuricaemia, genetic factors, dietary factors, alcohol consumption, metabolic syndrome, hypertension, obesity, diuretic use and chronic renal disease. Osteoarthritis predisposes to local crystal deposition. Gout appears to be an independent risk factor for all-cause mortality and cardiovascular mortality and morbidity, additional to the risk conferred by its association with traditional cardiovascular risk factors.

PMID:
21205285
PMCID:
PMC3046529
DOI:
10.1186/ar3199
[Indexed for MEDLINE]
Free PMC Article

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