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Vet Ophthalmol. 2011 Jan;14(1):66-8. doi: 10.1111/j.1463-5224.2010.00794.x.

Suitability and calibration of a rebound tonometer to measure IOP in rabbit and pig eyes.

Author information

1
Universität Rostock, Institut für Biomedizinische Technik, Friedrich-Barnwitz Str. 4, Rostock. marian.loebler@unirostock.de

Abstract

OBJECTIVE:

To utilize the Icare tonometer TAO1 for intraocular pressure (IOP) determination in experimental animals. To calculate true IOP calibration functions for rabbit and porcine eyes.

ANIMALS:

Enucleated eyes of 3-year-old healthy experimental rabbits (New Zealand white), and healthy 1 year old experimental pigs (Deutsche Landrasse) were used for the determination of IOP.

PROCEDURES:

Manometric (Geuder GmbH, Heidelberg/Germany) and rebound tonometry (Icare tonometer TAO1, Icare, Helsinki/Finland) were used to record IOP in enucleated animal eyes (rabbit n=2, pig n=3).

RESULTS:

The Icare tonometer TAO1 measurements underestimated true IOP by 37-60% in rabbit eyes and 17-63% in porcine eyes. IOP values obtained by both rebound and manometric tonometry for rabbit and porcine eyes followed a linear regression curve. Linear functions were calculated to correct the Icare tonometer TAO1 measurements to true IOP for both rabbit (p=1.4244p(ic) + 4.2421) and porcine eyes (p=1.0799p(ic) + 5.8557).

CONCLUSIONS:

The Icare tonometer TAO1 can be utilized for IOP determination in rabbit and porcine eyes when measured values are corrected with the appropriate linear function.

[Indexed for MEDLINE]

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