Format

Send to

Choose Destination
See comment in PubMed Commons below
Saudi J Gastroenterol. 2011 Jan-Feb;17(1):36-9. doi: 10.4103/1319-3767.74465.

Doppler assessment of hepatic venous waves for predicting large varices in cirrhotic patients.

Author information

1
Department of Medical Gastroenterology, Medical College, Thiruvananthapuram, Kerala, India. drthomasjos@yahoo.com.in

Abstract

BACKGROUND/AIM:

Color Doppler examination of changes in hepatic venous waveforms is being evaluated as a means of prediction of severity of portal hypertension and presence of esophageal varices. Normal hepatic venous waveform shows a triphasic pattern. In cirrhosis, this pattern changes to a biphasic or monophasic pattern. We aimed to study the sensitivity of loss of normal hepatic venous waveforms in predicting large varices in a cross-sectional analysis.

MATERIALS AND METHODS:

All patients, admitted or attending the outpatient department, with a diagnosis of cirrhosis were included in the study. All patients were subjected to oesophagogastroduodenoscopy and Color Doppler examination, and waveform patterns in hepatic vein were recorded. The sensitivity and specificity of changes in waveform in detecting large varices were studied.

RESULTS:

A total of 51 cases were examined. Triphasic waves were seen in 4 (7.8%) cases, biphasic in 26 (51%) cases, and monophasic in 21 (41.2%) cases. Small varices were seen in 30 (58.8%) cases and large varices in 21 (41.2%) cases. The sensitivity of loss of the triphasic wave pattern in detecting significant varices (Grade 3 or 4) was very high (95.23%) and negative predictive value was also high (75%). Severity of liver disease as indicated by Child-Pugh and MELD scores did not correlate with changes in hepatic venous waveforms.

CONCLUSION:

Loss of triphasic hepatic venous waveform is highly sensitive in predicting significant varices in patients with cirrhosis.

PMID:
21196651
PMCID:
PMC3099078
DOI:
10.4103/1319-3767.74465
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Medknow Publications and Media Pvt Ltd Icon for PubMed Central
    Loading ...
    Support Center