Format

Send to

Choose Destination
Nat Rev Microbiol. 2011 Feb;9(2):109-18. doi: 10.1038/nrmicro2475. Epub 2010 Dec 29.

Genetic control of Candida albicans biofilm development.

Author information

1
Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA.

Abstract

Candida species cause frequent infections owing to their ability to form biofilms - surface-associated microbial communities - primarily on implanted medical devices. Increasingly, mechanistic studies have identified the gene products that participate directly in the development of Candida albicans biofilms, as well as the regulatory circuitry and networks that control their expression and activity. These studies have uncovered new mechanisms and signals that govern C. albicans biofilm development and associated drug resistance, thus providing biological insight and therapeutic foresight.

PMID:
21189476
PMCID:
PMC3891587
DOI:
10.1038/nrmicro2475
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Nature Publishing Group Icon for PubMed Central
Loading ...
Support Center