Format

Send to

Choose Destination
J Neurosci Methods. 2011 Mar 15;196(1):118-23. doi: 10.1016/j.jneumeth.2010.12.022. Epub 2010 Dec 25.

Design of an in-dwelling cannula for convection-enhanced delivery.

Author information

1
Department of Neurosurgery, University of California San Francisco, 1855 Folsom St, MCB226, San Francisco, CA 94103-0555, USA.

Abstract

Failures of recent convection-enhanced delivery (CED) trials have underscored the need for improved CED cannulae. This study presents a novel in-dwelling cannula targeted for use in upcoming neuro-oncological or neurodegeneration trials. The cannula is reflux-resistant and easily integrated into clinical workflows. The cannula was evaluated in non-human primate CED studies performed with magnetic resonance imaging (MRI) to validate the effectiveness and safety of the infusion.

PMID:
21187114
DOI:
10.1016/j.jneumeth.2010.12.022
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center