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Genome Biol. 2010;11(12):R121. doi: 10.1186/gb-2010-11-12-r121. Epub 2010 Dec 23.

The Genomic HyperBrowser: inferential genomics at the sequence level.

Author information

1
Department of Informatics, University of Oslo, Blindern, 0316 Oslo, Norway. geirksa@ifi.uio.no

Abstract

The immense increase in the generation of genomic scale data poses an unmet analytical challenge, due to a lack of established methodology with the required flexibility and power. We propose a first principled approach to statistical analysis of sequence-level genomic information. We provide a growing collection of generic biological investigations that query pairwise relations between tracks, represented as mathematical objects, along the genome. The Genomic HyperBrowser implements the approach and is available at http://hyperbrowser.uio.no.

PMID:
21182759
PMCID:
PMC3046481
DOI:
10.1186/gb-2010-11-12-r121
[Indexed for MEDLINE]
Free PMC Article

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