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J Eukaryot Microbiol. 2011 Jan-Feb;58(1):75-6. doi: 10.1111/j.1550-7408.2010.00513.x. Epub 2010 Oct 12.

Evidence for a previously unrecognized mycobacterial endosymbiont in Acanthamoeba castellanii strain Ma (ATCC ® 50370 ™).

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Protistology Department, American Type Culture Collection, Manassas, Virginia 20110, USA.


We describe the isolation of a mycobacterium from Acanthamoeba castellanii strain Ma (ATCC(®) 50370(™)). The mycobacterium resides within vacuoles of A. castellanii, can be cultured by routine methodologies, and is a member of the Mycobacterium avium complex. Previously unrecognized mycobacterial endosymbionts are likely common among strains of Acanthamoeba housed at culture collections.

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