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Crit Care. 2010;14(6):1012. doi: 10.1186/cc9359. Epub 2010 Dec 20.

Beta 2 antagonism in acute respiratory failure.

Author information

1
Regional Intensive Care Unit, Royal Victoria Hospital, Grosvenor Road, Belfast, BT12 6BA, Northern Ireland.

Abstract

Post hoc analyses from the B-type natriuretic peptide for Acute Shortness of Breath Evaluation (BASEL)-II-ICU study suggest an association between beta-blocker usage at admission and improved mortality in patients treated in the intensive care unit for acute respiratory failure. Although this evidence is encouraging, there is a need for a phase 2 proof-of-concept randomized controlled trial of beta-blocker therapy in patients admitted with acute respiratory failure.

PMID:
21176173
PMCID:
PMC3220032
DOI:
10.1186/cc9359
[Indexed for MEDLINE]
Free PMC Article

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