Format

Send to

Choose Destination
See comment in PubMed Commons below
Org Lett. 2011 Feb 4;13(3):390-3. doi: 10.1021/ol102678j. Epub 2010 Dec 21.

An approach to the bis-oxazole macrocycle of diazonamides.

Author information

1
Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada.

Abstract

A convergent approach to a macrocyclic compound embodying the complete "eastern" quadrant of diazonamides is described. The opening sequence in this work relies on an oxazole-forming reaction devised earlier in this group, while a late step involves a Robinson-Gabriel cyclization of an amidoketone to form a second oxazole.

PMID:
21174393
DOI:
10.1021/ol102678j
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Chemical Society
    Loading ...
    Support Center