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J Pediatr Orthop. 2011 Jan-Feb;31(1 Suppl):S46-8. doi: 10.1097/BPO.0b013e3181fd87eb.

Update on prognostic genetic testing in adolescent idiopathic scoliosis (AIS).

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1
Genetics Research Laboratory, Axial Biotech, Inc., Salt Lake City, UT 84109, USA. jwogilvie@msn.com

Abstract

Case-control genome-wide association studies using a large, geographically diverse data base has been used to identify single nucleotide polymorphisms that have prognostic utility in predicting progression of mild adolescent idiopathic scoliosis in White patients. The calculated risk of progression score allows stratification of patients that can make medical care evidence based, less costly, and more efficient.

PMID:
21173618
DOI:
10.1097/BPO.0b013e3181fd87eb
[Indexed for MEDLINE]
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