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Neurol Clin. 2011 Feb;29(1):35-47, vii. doi: 10.1016/j.ncl.2010.10.008.

Traumatic brain injury and its neurobehavioral sequelae.

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Departments of Psychiatry and Neurology, Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1230, New York, NY 10029, USA.


The neurobehavioral sequelae of TBI consist of a spectrum of somatic, neurologic, and psychiatric symptoms. The challenge for clinicians lies in understanding the interface of the various symptoms and how they interrelate with other entities. Specifically, the challenge is differentiating post-TBI-related symptoms from preexisting or de novo psychiatric, neurologic, and/or systemic disorders. A comprehensive evaluation and a multidisciplinary approach to evaluating patients are essential to be able to develop the differential diagnosis needed to design a management plan that maximizes recovery.

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